Tryphena reminds me of something-- a chemical compound or a medical condition or something. I can't place it. It's pretty enough sounding, but it looks too clinical for me.
I once met a woman named Adelphi (a DEL fee, not a del fye like the town in NY) that I thought was pretty.
Philadelphia has a nice sound, and a great meaning, but yeah, I just think of the city. I probably wouldn't name a kid Chicago or Baltimore for the same reason. But then, Boston is apparently climbing the charts for kids these days and
Austin and
Dallas are already established, so why not?