I like the sound of it and it has a nice uplifting meaning. I get the appeal, but wouldn't consider it as a real name. I like it the same way I like Revolution, Troubadour or Carillon. Lovely sounds and vibes to me, but strictly in the realm of GP. For the record, this is the sound I love:
https://forvo.com/word/renaissance/#fr. I've heard different pronunciations, but I like it most with this sound.
If I'd met a girl named Renaissance, I'd think the parents were trying too hard. On the other hand, it's way better than many names like
Nevaeh (or worse Neveah),
Emersyn or Mckinley. I'd rather be called Renaissance any day.
Combo suggestions:
Renaissance
ValentineRenaissance
JulietteRenaissance
PhilomelRenaissance
Amélie Renaissance
MagaliRenaissance
Nathalie Estelle Renaissance
Valerie Renaissance
Ophelia Renaissance
Philomena Renaissance
Séraphine Renaissance
I wouldn't pair with anything too short, bc then the combo feels off balance to me.
PS. You've misspelled Renaissance 7 times in your post ;)